Siddharth (Abhishek Bachchan) finds himself at a stage in life where this Run assumes significance like never before. Leaving behind his cocoon in Agra he reaches Delhi hoping to turn his aspirations into reality. Here he meets the beautiful Jhanavi (Bhoomika Chaula) whose innocence takes his breath away. But little does he know that she carries with her an excess baggage that threatens to take his life away. This excess baggage is Jhanavi's demonic brother Ganpat Choudhry (Mahesh Manjrekar) whose possessiveness of his sister spells pure poison. That hand that dares to touch Jhanavi's heart just has to be cut. But Siddharth is the owner of awe-inspiring might that is hard to ignore. And thus begins a racy battle of one- up man ship between the two equally motivated men. Both of whom are used to getting what they want. Anytime. Every time. No matter what……..!! Ganpat leaves no stone unturned to make life hell for Siddharth. Finally something fateful happens and Siddharth devises a foolproof way to combat the devious Ganpat .A way that has no parallel……. It is this unique way that will make Siddharth's Run a victorious one. And true victory is attained only when the Run ends…. Run is a simple film about complex situations, in which people learn different things about life, about themselves and about others. In a breezy fashion it will make you love & hate, Laugh & cry, live & learn.